T0901317是一个强的和选择性的LXR和FXR激动剂，EC50分别是50 nM和5 μM，能够抑制核里的NF/κB。A cell-permeable, nonsterol compound that acts as a highly potent LXR activator T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. A cell-permeable, nonsterol compound that acts as a highly potent LXR activator