2-Bromo-3-hydroxy-4-methoxybenzaldehyde, also known as 2-bromo-isovanillin, can be synthesized by the bromination of 3-hydroxy-4-methoxybenzaldehyde. Application： 2-Bromo-3-hydroxy-4-methoxybenzaldehyde (2-Bromo-isovanillin) may be used in the preparation of: 2-hydroxy-3-methoxybenzaldehyde semicarbazone (HMBS) 2-cyclopentyl-7-methoxy-1-benzofuran-4-carbaldehyde 3-(benzyloxy)-2-bromo-4-methoxybenzaldehyde