Equisetin是一种由N-甲基丝氨酸衍生的酰基四酸，由多种具有抗生素和细胞毒性活性的F产生。该化合物在体外对线粒体ATP酶和HIV-1具有抑制活性。在对酿酒酵母中的线粒体无机焦磷酸酶（PPase）的研究中，观察到Equisetin使线粒体PPase活性增加了数倍。数据表明，Equisetin特异性抑制线粒体内膜的底物阴离子载体，同时非特异性地作用于蛋白膜和蛋白疏水域。 Equisetin is an N-methylserine-derived acyl tetramic acid produced by a number of|Fusarium|species with antibiotic and cytotoxic activity. The compound has displayed inhibitory activity against mitochondrial ATPases and HIV-1 integrase|in vitro|. In a study of mitochondrial inorganic pyrophosphatase (PPase) in the yeast|Saccharomyces cerevisiae|, Equisetin is observed to increase mitochondrial PPase activity several folds. Data has shown that Equisetin specifically inhibits the substrate anion carriers of the inner membrane of mitochondria while acts nonspecifically on protein membranes and protein hydrophobic domains.