Taprenepag isopropyl, 类前列腺素 EP2 受体激动剂

小分子

塔普尼帕异丙酯

Taprenepag isopropyl [USAN] | 4-O- beta -D-Mannopyranosyl-D-glucopyranoside | isopropyl [3-({[4-(1H-pyrazol-1-yl)benzyl](pyridin-3-yl-sulfonyl)amino}methyl)phenoxy]acetate | isopropyl [3-({[4-(1H-pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl)-amino}methyl)phe

Taprenepag isopropyl

T648100-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

Taprenepag isopropyl is a highly selective EP 2 receptor agonist. In Vivo Taprenepag isopropyl is a highly selective EP 2 receptor agonist. Intraocular pressure (IOP) in the left, vehicle-dosed eye typically remains within the normal range. In the right (Taprenepag isopropyl-dosed) eye, IOP is reduced in all dose groups. In the high-dose group, IOP is reduced to the extent that it cannot be measured ( Form:Solid IC50& Target:EP2

Taprenepag isopropyl 是一种高选择性 EP 2 受体激动剂。

1005549-94-9

C27H28N4O5S

520.6 g/mol

23729077

CC(C)OC(=O)COC1=CC=CC(=C1)CN(CC2=CC=C(C=C2)N3C=CC=N3)S(=O)(=O)C4=CN=CC=C4

propan-2-yl 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]phenoxy]acetate

1S/C27H28N4O5S/c1-21(2)36-27(32)20-35-25-7-3-6-23(16-25)19-30(37(33,34)26-8-4-13-28-17-26)18-22-9-11-24(12-10-22)31-15-5-14-29-31/h3-17,21H,18-20H2,1-2H3

NVPXUFQLKWKBHK-UHFFFAOYSA-N

CC(C)OC(=O)COC1=CC=CC(=C1)CN(CC2=CC=C(C=C2)N3C=CC=N3)S(=O)(=O)C4=CN=CC=C4

23729077

DMSO : 200 mg/mL (384.17 mM; Need ultrasonic)

0

8

12

520.178 Da

520.178 Da

112.000 Ų

37

0

812

0

1

3.6

激动剂

类前列腺素 EP2 受体激动剂

NONHforallmodesoftransport