TUG-1375

小分子

TUG-1375

T649206-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

TUG-1375 is an agonist of free fatty acid receptor 2 ( FFA2/GPR43 ), with a pK i of 6.69. TUG-1375 is inactive on FFA3, FFA4, PPARα , PPARγ , PPARδ , LXRα or LXRβ In Vitro TUG-1375 exhibits pEC 50 of 7.11 in the cAMP FFA2 assay, also active on murine FFA2 orthologue (pEC 50 , 6.44 ± 0.13 in the cAMP assay). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:pKi: 6.69 (FFA2)

TUG-1375 是游离脂肪酸受体 2（FFA2/GPR43）的激动剂，pK i 为 6.69。TUG-1375 对 FFA3、FFA4、PPARα、PPARγ、PPARδ、LXRα 或 LXRβ 均无活性。

2247372-59-2

C22H19ClN2O4S

442.9 g/mol

138319694

CC1=C(C(=NO1)C)C2=CC=C(C=C2)C(=O)N3[C@@H](CS[C@@H]3C4=CC=CC=C4Cl)C(=O)O

(2R,4R)-2-(2-chlorophenyl)-3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzoyl]-1,3-thiazolidine-4-carboxylic acid

1S/C22H19ClN2O4S/c1-12-19(13(2)29-24-12)14-7-9-15(10-8-14)20(26)25-18(22(27)28)11-30-21(25)16-5-3-4-6-17(16)23/h3-10,18,21H,11H2,1-2H3,(H,27,28)/t18-,21+/m0/s1

RZAMDGBOOPJHJQ-GHTZIAJQSA-N

CC1=C(C(=NO1)C)C2=CC=C(C=C2)C(=O)N3C(CSC3C4=CC=CC=C4Cl)C(=O)O

138319694

DMSO : 125 mg/mL (282.22 mM; Need ultrasonic)

1

6

4

442.075 Da

442.075 Da

109.000 Ų

30

0

645.000

0

1

4.600