Thalidomide-PEG3-COOH

沙利度胺-PEG3-COOH

Thalidomide-PEG3-COOH

T658943-50mg

50mg

≥98%

避光,-20°C储存

超低温冰袋运输

Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Appearance:Solid IC50& Target:Cereblon In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

C20H22N2O9

434.4 g/mol

O=C1N(C2C(NC(CC2)=O)=O)C(C3=CC=C(OCCOCCOCCC(O)=O)C=C31)=O

DMSO : 250 mg/mL (575.51 mM; Need ultrasonic)