Thalidomide-Propargyne-PEG3-COOH

沙利度胺-炔丙基-PEG3-COOH

Thalidomide-Propargyne-PEG3-COOH

T659220-50mg

50mg

≥98%

避光,-20°C储存,干燥

超低温冰袋运输

Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Appearance:Viscous liquid IC50& Target:Cereblon In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

C23H24N2O9

472.44 g/mol

OC(CCOCCOCCOCC#CC(C=C12)=CC=C2C(N(C1=O)C3CCC(NC3=O)=O)=O)=O

DMSO : 100 mg/mL (211.67 mM; Need ultrasonic)