Adenine 9-β-D-arabinofuranoside (AraA) is a nucleoside analog. It is an antiviral drμg and targets viral DNA polymerases and is majorly used for treating herpes simplex viral infection. It is a potent inhibitor of AMP-activated protein kinase (AMPK).It also inhibits cardiac type 5 adenylyl cyclase but does not improve pathology in cardiovascular diseasesAdenine 9-β-D-arabinofuranoside has been used for the inhibition of 5′ AMP-activated protein kinase (AMPK) in liver, muscle and cardiac cells H9c2. Adenine 9-β-D-arabinofuranoside (AraA) is a nucleoside analog. It is an antiviral drug and targets viral DNA polymerases and is majorly used for treating herpes simplex viral infection. It is a potent inhibitor of AMP-activated protein kinase (AMPK).It also inhibits cardiac type 5 adenylyl cyclase but does not improve pathology in cardiovascular diseases