Masitinib (AB1010)是一种新型的Kit和PDGFRα/β抑制剂，IC50分别为200 nM和540 nM/800 nM，但对ABL和c-Fms抑制作用较弱。Phase 3A tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor. Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3. A tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor.