USP7-IN-1

未知

USP7-IN-1

U648748-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7) , with an IC 50 of 77 μM, and can be used for the research of cancer . In Vitro USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC 50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI 50 of 67 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 77 μM (USP7)

USP7-IN-1 是泛素特异性蛋白酶 7（USP7）的一种选择性可逆抑制剂，IC 50 为 77 μM，可用于癌症研究。

1381291-36-6

C23H24ClN3O3

425.91 g/mol

71278663

C1CN(CCC1(CN2C=NC3=C(C2=O)C=CC(=C3)Cl)O)C(=O)CCC4=CC=CC=C4

7-chloro-3-[[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl]quinazolin-4-one

1S/C23H24ClN3O3/c24-18-7-8-19-20(14-18)25-16-27(22(19)29)15-23(30)10-12-26(13-11-23)21(28)9-6-17-4-2-1-3-5-17/h1-5,7-8,14,16,30H,6,9-13,15H2

CITWIBXKKHFDFM-UHFFFAOYSA-N

C1CN(CCC1(CN2C=NC3=C(C2=O)C=CC(=C3)Cl)O)C(=O)CCC4=CC=CC=C4

71278663

DMSO : 100 mg/mL (234.79 mM; Need ultrasonic)

1

4

5

425.151 Da

425.151 Da

73.200 Ų

30

0

656.000

0

1

2.600