红霉素B（12-脱氧红霉素A）是通过发酵红霉素放线菌（Saccharopolyspora erythreae）产生的红霉素次要共代谢物。尽管红霉素B比红霉素A效力低，但它具有广谱的抗生素活性。红霉素B在半合成红霉素的结构活性关系研究中起着不可或缺的作用，但没有到临床阶段。 Erythromycin B (12-deoxyerythromycin A) is a minor co-metabolite of erythromycin produced by fermentation of Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity,albeit less potent than erythromycin A. Erythromycin B played an integral part of the structure activityrelationship studies of semi-synthetic erythromycins, however none reached clinical development.