Dorsomorphin 2HCl是一种有效的，可逆的AMPK选择性抑制剂，Ki为109 nM，对一些结构相关的激酶，包括ZAPK， SYK， PKCθ， PKA和JAK3没有显著的抑制作用。同时抑制了BMP一型受体作用。A potent and selective AMPK inhibitor. Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits BMP type I receptor. A potent and selective AMPK inhibitor.