叶酸-PEG-胺，也称为叶酸-PEG-amine，是一种具有伯胺基团的Nanocs反应性叶酸-PEG衍生物。伯胺可以与多种官能团反应，如琥珀酰亚胺酯（NHS）、羧酸（COOH）、酸酐和许多其他官能团。该反应允许叶酸配体附着于蛋白质、抗体、肽或颗粒表面。聚乙二醇化叶酸具有较好的水溶性和生物活性。叶酸功能化底物已被用于靶向药物递送、成像和生物测定开发。 Folic acid PEG amine, also called Folate PEG amine, is one of Nanocs reactive folic acid PEG derivatives with a primary amine group. Primary amine can react with a variety of functional groups such as succinimidyl ester (NHS), carboxylic acids (COOH), anhydride and many others. This reaction allows attachment of folic acid ligand to proteins, antibodies, peptides or particle surfaces. Pegylated folic acid has relatively good water solubility and bioactivity. Folic acid functionalized substrates have been used for targeted drug delivery, imaging, and bioassay development.