GSK1790627 is the N-deacetylated metabolite of Trametinib . Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis. In Vitro GSK1790627 (1, 10 and 50 μM, 60 min) is stable in the presence of recombinant hNAT enzymes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid