Trimethoxy[3-(methylamino)propyl]silane was coated onto a substrate for the preparation of gold dimers by aggregating gold nanospheres. The silane may be used as a silane coupling agent to prepare silica nanoparticles. 2 It may be used to modify quartz substrates. Trimethoxy[3-(methylamino)propyl]silane was coated onto a substrate for the preparation of gold dimers by aggregating gold nanospheres. The silane may be used as a silane coupling agent to prepare silica nanoparticles. 2 It may be used to modify quartz substrates.