Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen . Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides In Vitro Angiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides. Angiotensinogen isolated from most species is cleaved by human renin. Synthetic peptides containing the N-terminal amino-acid sequence of angiotensinogen were renin substrates. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Human Endogenous Metabolite