免疫球蛋白M,μ链,人血浆

np001053-250μg

250μg

≥95%(SDS-PAGE)

用1.0 M乙酸复溶至冻干前体积。必须用醋酸稀释。 IgM重链（μ链）由576个氨基酸组成；每个IgM分子中有5μ链。IgM重链是通过还原连接它与IgMκ和λ轻链的二硫键来纯化的。IgMμ链在不同物种之间比IgG或IgA的重链更为保守。 由经美国食品药品监督管理局要求的测试显示对HBsAg、抗-HCV、抗-HBc无反应且对抗-HIV 1和2呈阴性的血浆制备。 Ref: Hayzer, D. J., and Jaton, J-C. 1985. Methods Enzymol. 116, 16; Jeske, D. J., and Capra J. D. 1984. Fundamental Immunology (W.E. Paul, ed.), 131. Reconstitute with 1.0 M acetic acid to the pre-lyophilization volume. Dilutions must be made in Acetic Acid. IgM heavy chain (mu chain) consists of 576 amino acids; there are five mu chains in each IgM molecule. IgM heavy chain is purified by reducing the disulfide bond connecting it to the IgM kappa and lambda light chains. IgM mu chain is more highly conserved across different species than is the heavy chain of IgG or IgA. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. Ref: Hayzer, D. J., and Jaton, J-C. 1985. Methods Enzymol. 116, 16; Jeske, D. J., and Capra J. D. 1984. Fundamental Immunology (W.E. Paul, ed.), 131.

75,000Da