免疫球蛋白E(IgE),人骨髓瘤血浆,Lambda

np001078-25μg

25μg

≥95%(SDS-PAGE)

在pH 7.4的15 mM磷酸钾中冷冻，含有150 mM NaCl和0.05%NaN3。 IgE是血浆中含量最低的免疫球蛋白，其浓度低于正常血浆的0.6微克/毫升。在经历严重过敏反应和寄生虫感染的患者中发现IgE水平升高。在骨髓瘤的情况下，IgE是由单个浆细胞克隆产生的。然而，骨髓瘤IgE的结构是正常的，从骨髓瘤来源纯化的免疫球蛋白是研究免疫球蛋白行为的有用蛋白质。 Lambda由人骨髓瘤血浆制备，经美国食品药品监督管理局要求的测试显示，Lambda对HBsAg、抗HCV、抗HBc无反应，对抗HIV 1和2呈阴性。 Frozen in 15 mM potassium phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3. IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior. Prepared from human myeloma plasma, Lambda shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

190000