血液结合素,大鼠血清

np001085-25μg

25μg

≥95%(SDS-PAGE)

血红蛋白是一种单链蛋白，属于血液转运蛋白家族。它与降解过程中释放到血液中的血红素结合。最近的研究表明，血红素环素是一种细胞外抗氧化剂，可以对抗血红蛋白介导的炎症损伤。Hemopexin可以防止血红素毒性，保存和回收铁。血红素水平异常与溶血性贫血、慢性神经肌肉疾病和急性间歇性卟啉症有关。 由雅典研究与技术实验室的大鼠血清制备。 原产国：大鼠血清来源于美国健康动物，由注册兽医护理。 产品引用： Vercellotti GM, Zhang P, Nguyen J, Abdulla F, et al. Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease. Mol Med. 2016 Jul 19;22. doi: 10.2119/molmed.2016.00063. [Epub ahead of print] Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria. Prepared from Rat Serum in the Athens Research & Technology laboratory. Country of Origin: Rat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian. Product Citation: Vercellotti GM, Zhang P, Nguyen J, Abdulla F, et al. Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease. Mol Med. 2016 Jul 19;22. doi: 10.2119/molmed.2016.00063. [Epub ahead of print]