抗凝血酶III 来源于人血浆

ATIII, Antithrombin, AT, Factor Xa inhibitor, Heparin cofactor

np001141-25μg

25μg

BioReagent

≥95%(SDS-PAGE)

在正常血清中，抗凝血酶 Ⅲ 的含量为每 100 毫升 15 毫克。由于在凝血过程中会与凝血酶形成复合物，其在血浆中的含量高于血清。 抗凝血酶 Ⅲ 的功能是抑制参与血液凝固和纤维蛋白溶解的蛋白水解酶，包括 Xa 因子、纤溶酶、凝血酶和胰蛋白酶。肝素能显著增强其活性。 在临床上，抗凝血酶 Ⅲ 水平降低提示存在高凝状态。 消光系数：0.65 所用血浆经 FDA 要求的检测显示，乙型肝炎表面抗原（HBsAg）、抗丙型肝炎病毒（抗 - HCV）、抗乙型肝炎核心抗体（抗 - HBc）均为阴性，且抗人类免疫缺陷病毒 1 型和 2 型（抗 - HIV 1 & 2）也为阴性。 Antithrombin III is found in normal serum at 15 mg per 100 ml. Found at higher levels in plasma than in serum because of complexing with thrombin during coagulation. Functions in the inhibition of the proteolytic enzymes involved in blood coagulation and fibrinolysis, including factor Xa, plasmin, thrombin, and trypsin. Potency is strongly enhanced by heparin. Clinically, reduced levels are indicative of hypercoagulability. Extinction Coefficient: 0.65 Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

天然

58 kDa

人(Human)