α2-抗纤维蛋白溶酶 来源于人血浆

np001160-25μg

25μg

BioReagent

≥95%(SDS-PAGE)

有效抑制纤溶酶原激活物诱导的纤维蛋白凝块溶解。血浆中发现的α-抗纤溶酶缺乏症约为每毫升70微克，是一种罕见的凝血障碍，允许不受限制的纤溶活性。患有这种疾病的人可以在手术前接受治疗性A2AP，以防止术后出血。 消光系数： 0.703 所用血浆经 FDA 要求的检测显示，乙型肝炎表面抗原（HBsAg）、抗丙型肝炎病毒（抗 - HCV）、抗乙型肝炎核心抗体（抗 - HBc）均为阴性，且抗人类免疫缺陷病毒 1 型和 2 型（抗 - HIV 1 & 2）也为阴性。 Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Found in plasma at about 70 ug per ml. Alpha-antiplasmin-deficiency is a rare coagulation disorder which allows unrestrained fibrinolytic activity. Individuals with this condition may receive therapeutic A2AP prior to surgery to prevent postoperative hemorrhaging. Extinction Coefficient: 0.703 Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. Post-translational: Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin.

≥5.0 U/mg

天然

70 kDa

人(Human)