Recombinant Human Activin RIIA Protein

激活素A受体ⅡA(ACVR2A)重组蛋白 | 重组人类激活素 RIIA 蛋白

Activin receptor type IIA | ACTRIIA | ACTR-IIA | EC 2.7.11.30 | Activin A receptor type IIA | Activin receptor type 2A | Activin receptor type IIA | Activin receptor type-2A | ACTR 2 | ACTR IIA | ACTR-IIA | ACTR2 | ACTRII | ACTRIIA | Acvr 2A | Acvr 2 | Ac

rp142510-10μg

10μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.

重组表达

13 kDa

C-His

30.0 - 35.0 kDa, under reducing conditions; 30.0 - 35.0 kDa, under non-reducing conditions.

HEK293 Accession #: P27037-1 | HEK293

<0.1 EU/μg

人(Human)

20-134 aa

AILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPHHHHHH

Yes

Yes