Recombinant Human ARMET/ARP Protein

重组人 ARMET/ARP 蛋白 | 重组人类 ARMET/ARP 蛋白

Arginine rich mutated in early stage tumors | Arginine rich protein | Arginine-rich protein | ARMET | ARMET protein | ARP | Manf | MANF_HUMAN | Mesencephalic astrocyte derived neurotrophic factor | Mesencephalic astrocyte-derived neurotrophic factor | MGC

rp142973-50μg

50μg

无动物源

≥95%(SDS-PAGE&HPLC)

＞95%(SDS-PAGE and HPLC)

Purity >95% by SDS-PAGE and HPLC analyses. Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. Post-translational May contain sialic acid residues.

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/ml, corresponding to a specific activity of > 50 IU/mg.

重组表达

18.2 kDa

No tag

18.2 kDa

Full length protein

E. coli Accession #: P55145 | E. coli

<1.0 EU/μg

人(Human)

25-182aa

LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL

Yes

Yes