Recombinant Human BDNF GMP Protein

重组人BDNF蛋白 | 重组人脑源性神经营养因子蛋白

Abrineurin | BDNF | Abrineurin | ANON2 | BDNF | brain-derived neurotrophic factor | BULN2 | MGC34632 | Neurotrophin | Abrineurin | ANON2 | BDNF | brain-derived neurotrophic factor | BULN2 | MGC34632 | Neurotrophin

rp143209-GMP-25μg

25μg

无动物源

≥70%(SDS-PAGE)

Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

The activity is determined by the dose-dependent proliferation of C6 cell sand is typically between 0.5-1.5 ug/mL. Corresponding to a specific Activity of 1 x 10^3 units/mg.

重组表达

13.5 kDa

No tag

12 kDa, under reducing conditions.

CHO Accession #: P23560-1 | CHO

<10 EU/mg

人(Human)

129-247 aa

HSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

Yes

Yes

Met-Arg134-Arg-Gly-Glu-Leu-Ser-Val-(Cys)-Asp