Recombinant Human BMPR-IA/ALK-3 Protein

骨成型蛋白受体1A(BMPR1A)重组蛋白

Activin receptor-like kinase 3 | ALK-3 | BMP type-1A receptor | BMPR-1A | EC 2.7.11.30 | Serine/threonine-protein kinase receptor R5 | SKR5 | ACVRLK310q23del | ALK-3 | ALK3EC 2.7.11.30 | BMP type-1A receptor | BMPR1A | BMPR-1A | BMPRIA | BMPR-IA | bone mo

rp143319-10μg

10μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

Immobilized Human ACVR2B at 1 μg/mL (100 μL/well) can bind Human BMPRIA with a linear range of 0.5-62.5 ng/mL

重组表达

15 kDa

C-His

28-33 kDa, under reducing conditions

HEK293 Accession #: P36894 | HEK293

<0.1 EU/μg

人(Human)

24-152 aa

QNLDSMLHGTGMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPVVIGPFFDGSIRHHHHHH

Yes

Yes