Recombinant Human CD276 Protein

重组人CD276蛋白 | 重组人 CD276 蛋白

B7H3 | B7-H3 | B7H34Ig-B7-H3 | B7-H3B7 homolog 3 | CD276 antigen | CD276 molecule | CD276 | Costimulatory molecule | B7RP-2 | 4Ig-B7-H3

rp143912-50μg

50μg

无动物源

≥95%(SDS-PAGE)

＞95% (SDS-PAGE)

Purity >95% SDS-PAGE Function May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

1、Immobilized Recombinant Human CD276 Protein (rp143912) at 0.5 μg/mL can bind Anti Human CD276 Antibody with the EC50 of 10.73 ng/mL. 2、Immobilized Recombinant Human CD276 Protein (rp143912) at 1 μg/mL can bind Anti Human CD276 Antibody with a linear range of 1 - 4 ng/mL (EC50:4.3 ng/mL).

重组表达

23 kDa

C-His

38.9 kDa, under reducing conditions; 37.0 kDa, under non-reducing conditions.

HEK293 Accession #: Q5ZPR3-2 | HEK293

<0.1 EU/μg

人(Human)

29-246 aa

LEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPHHHHHH

Yes

Yes