Recombinant Human Fc gamma RIIB/CD32b Protein

IgG-Fc片段低亲和力受体Ⅱb(FcgR2B)重组蛋白

CDw32 | Fc-gamma RII-b | Fc-gamma-RIIb | FcRII-b | IgG Fc receptor II-b | CD32 | CD32 antigen | CD32B | CDw32 | Fc fragment of IgG, low affinity II, receptor for (CD32) | Fc fragment of IgG, low affinity IIb, receptor | Fc fragment of IgG, low affinity II

rp143962-10μg

10μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Immobilized Recombinant Human FCGR2B at 2 μg/mL (100 μL/well) can bind biotinylated Human IgG1 with a linear range of 0.0048-2.81 μg/mL.

重组表达

20 kDa

C-His

27 - 32 kDa, under reducing conditions; 25 - 30 kDa, under non-reducing conditions.

HEK293 Accession #: P31994 | HEK293

<0.1 EU/μg

人(Human)

46-217 aa

APPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPHHHHHH

Yes

Yes