Recombinant Human CDNF Protein

脑多巴胺神经营养因子(CDNF)活性蛋白

ARMET-like protein 1 | Conserved dopamine neurotrophic factor | ARMETL1 | ARMET-like protein 1 | CDNF | cerebral dopamine neurotrophic factor | Conserved dopamine neurotrophic factor | arginine-rich, mutated in early stage tumors-like 1

rp144239-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Able to significantly enhance neurite outgrowth when immobilized at 6-24 µg/mL on a nitrocellulose-coated microplate.

重组表达

19.9 kDa

C-10His

19 & 25 kDa, under reducing conditions; 19 & 25 & 37 kDa, under non-reducing conditions.

HEK293 Accession #: Q49AH0 | HEK293

<0.1 EU/μg

人(Human)

25-187 aa

QGQEAGGRPGADCEVCKEFLNRFYKSLIDRGVNFSLDTIEKELISFCLDTKGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEKLKKLDSQICELKYEKTLDLASVDLRKMRVAELKQILHSWGEECRACAEKTDYVNLIQELAPKYAATHPKTELHHHHHHHHHH

Yes

Yes