Recombinant Human CCL11/Eotaxin Protein

重组人嗜酸粒细胞趋化因子 | 重组人 CCL11/Eotaxin 蛋白

C-C motif chemokine 11 | CCL11 | chemokine (C-C motif) ligand 11 | Eosinophil chemotactic protein | Eotaxin | eotaxin-1 | MGC22554 | SCYA11Small-inducible cytokine A11 | small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) | SCYA11 | C-C mo

rp145581-50μg

50μg

无动物源

≥97%(SDS-PAGE&HPLC)

＞97%(SDS-PAGE, HPLC)

Purity > 97 % by SDS-PAGE and HPLC analyses.Endotoxin level is Function Human CCL11 is belonging to the CC chemokine family. It is encoded by the gene CCL11. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. CCR3 has been identified to be a specific CCL11 receptor.In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml.

重组表达

8.4 kDa

No tag

Full length protein

E. coli Accession #: P51671 | E. coli

<1.0 EU/μg

人(Human)

24-97 aa

GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP

Yes

Yes