Recombinant Human GFR alpha-2/GFRA2 Protein

胶质细胞系来源神经营养因子受体α2(GFRa2)重组蛋白 | 重组人 GFR alpha-2/GFRA2 蛋白

GDNF family receptor alpha 2 | GDNF family receptor alpha-2 | GDNF receptor alpha-2 | GDNF receptor beta | GDNFR beta | GDNFR-alpha-2 | GDNFR-beta | GDNFRB | GFR alpha 2 | GFR-alpha-2 | GFRA 2 | Gfra2 | GFRA2_HUMAN | Glial cell line derived neurotrophic f

rp146403-10μg

10μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.

Immobilized Recombinant Human Neurturin Protein at 5.0 μg/mL can bind Recombinant Human GFR alpha-2/GFRA2 Protein (rp146403), the EC50 of this effect is 1.99 μg/mL.

重组表达

47 kDa

C-His

75.0 kDa, under reducing conditions; 70.0 kDa, under non-reducing conditions.

HEK293 Accession #: O00451-1 | HEK293

<0.1 EU/μg

人(Human)

22-441 aa

SPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSHHHHHH

Yes

Yes