Recombinant Human Progranulin Protein

颗粒体蛋白(GRN)重组蛋白

Acrogranin | Epithelin precursor | Glycoprotein 88 | Glycoprotein of 88 Kda | GP88 | Granulin precursor | PC cell-derived growth factor | PCDGF | PEPI | PGRN | Proepithelin | Acrogranin | CLN11 | GEP | GP88 | Granulin A | Granulin B | Granulin C | Granuli

rp146631-10μg

10μg

无动物源

≥92%(SDS-PAGE)

Purity ≥92% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.

Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Recombinant Human Progranulin/PGRN, immobilized at 10-40 μg/mL on a nitrocellulose coated plate, is able to significantly enhance neurite outgrowth.

63 kDa

C-His

90-95 kDa, under reducing conditions

HEK293 Accession #: P28799 | HEK293

<0.1 EU/μg

人(Human)

18-593 aa

TRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLLHHHHHH

Yes

Yes