Recombinant Human IGF-1 Protein

重组人IGF-1蛋白 | 重组人胰岛素样生长因子1蛋白

IGF-I | Mechano growth factor | MGF | Somatomedin-C

rp147252-500μg

500μg

无动物源

≥95%(SDS-PAGE)

＞95% SDS-PAGE

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.

Measured in a cell proliferation assay using MCF7 breast cancer cell line. The ED₅₀ for this effect is typically <4.6 ng/mL.

重组表达

7.7 kDa

No tag

8.5 kDa, under reducing conditions; 8.5 kDa, under non-reducing conditions.

Full length protein

毕赤酵母 Accession #: P05019 | 毕赤酵母

<0.2 EU/μg

人(Human)

49-118 aa

GP ETLCGAELVD ALQFVCGDRG FYFNKPTGYG SSSRRAPQTG IVDECCFRSC DLRRLEMYCA PLKPAKSA

Yes

Yes

Gly