Recombinant Human IL-28A/IFN-lambda 2 Protein

重组人白细胞介素28A蛋白 | 重组人 IL-28A/IFN-lambda 2 蛋白

interleukin-28A | IFN-lambda 2 | IL28A | IL-28A | interferon, lambda 2 | IFNL2a | IFNL3a

rp147532-5μg

5μg

无动物源

≥95%(SDS-PAGE)

＞95% (SDS-PAGE)

Purity >95% SDS-PAGE. Endotoxin level is less than 0.1EU/μg. Function Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED₅₀ for this effect is 5-30 ng/mL.

重组表达

20 kDa

C-His

21.1 kDa, under reducing conditions; 16.5 kDa, under non-reducing conditions.

HEK293 Accession #: Q8IZJ0 | HEK293

<0.1 EU/μg

人(Human)

26-200 aa

VPVARLHGALPDARGCHIAQFKSLSPQELQAFKRAKDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALVDVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTFNLFRLLTRDLNCVASGDLCVHHHHHH

Yes

Yes