Recombinant Human LILRB2/CD85d/ILT4 Protein

白细胞免疫球蛋白样受体亚家族B成员2(LILRB2)重组蛋白

CD85 antigen-like family member D | CD85d antigen | CD85d | Ig-like transcript 4 | ILT4 | ILT-4 | ILT4CD85d | Immunoglobulin-like transcript 4 | Leukocyte immunoglobulin-like receptor 2 | leukocyte immunoglobulin-like receptor subfamily B member 2 soluble

rp147662-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Measured by its binding ability in a functional ELISA. When Recombinant Human LILRB2/ILT4 Protein (rp147662) is coated at 2 µg/mL can bind Recombinant Human Angiopoietin-like Protein 7/ANGPTL7, the ED50 for this effect is 326.7 ng/mL.

重组表达

48 kDa

C-His

62 - 72 kDa, under reducing conditions; 62 - 72 kDa, under non-reducing conditions.

HEK293 Accession #: Q8N423-1 | HEK293

<0.1 EU/μg

人(Human)

22-458 aa

QTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHHHHHHH

Yes

Yes