Recombinant Human AMICA Protein

连接粘附分子样蛋白重组蛋白

adhesion molecule, interacts with CXADR antigen 1 | AMICA | AMICA1 | CREA7-1 | Gm638 | JAML | CREA7-4 | Dendritic cell-specific protein CREA7-1 | dendritic-cell specific protein CREA7-1 | dendritic-cell specific protein CREA7-4 | Junctional adhesion molec

rp147886-10μg

10μg

无动物源

≥90%(SDS-PAGE)

May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.

Measured by the ability of the immobilized protein to support the adhesion of BT‑20 human breast cancer cells. When 5 x 10^4 cells/well are added to rhJAML coated plates (10 µg/mL, 100 µL/well), approximately 55%-75% will adhere after 1 hour at 37° C. Similar results were obtained using HeLa, A549, and T84 cell-lines. Optimal dilutions should be determined by each laboratory for each application.

重组表达

29.7 kDa

C-His

43 kDa, under reducing conditions

HEK293 Accession #: Q86YT9 | HEK293

<0.1 EU/μg

人(Human)

10-265 aa

LPVLLDYSLGLNDLNVSPPELTVHVGDSALMGCVFQSTEDKCIFKIDWTLSPGEHAKDEYVLYYYSNLSVPIGRFQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFKKAVVLHVLPEEPKELMVHVGGLIQMGCVFQSTEVKHVTKVEWIFSGRRAKEEIVFRYYHKLRMSVEYSQSWGHFQNRVNLVGDIFRNDGSIMLQGVRESDGGNYTCSIHLGNLVFKKTIVLHVSPEEPRTLVTPAALHHHHHH

Yes

Yes