Recombinant Human MAG/Siglec-4a Protein

重组人MAG/Siglec-4a蛋白 | 重组人髓鞘关联糖蛋白蛋白 | 重组人MAG/Siglec-4a蛋白 | 重组人髓鞘关联糖蛋白蛋白 | 重组人MAG/Siglec-4a蛋白 | 重组人髓鞘关联糖蛋白蛋白

Siglec-4a | GMA | sialic acid binding Ig-like lectin 4A | MAG | myelin associated glycoprotein | myelin-associated glycoprotein | sialic acid-binding immunoglobulin-like lectin 4A | Siglec4a | Siglec-4a | S-MAG | SPG75 | SIGLEC4 | sialic acid binding Ig-l

rp148491-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid.

Measured by its ability to inhibit neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. When immobilized as a 3 µL droplet containing 200 ng on a nitrocellulose coated microplate, Recombinant Human MAG/Siglec4a Fc Chimera is able to significantly inhibit neurite outgrowth.

重组表达

82 kDa

C-hFc

113 kDa under reducing conditions.

HEK293 Accession #: P20916 | HEK293

<0.1 EU/μg

人(Human)

20-516 aa

GHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Yes

Yes