Recombinant Human MICA Protein

Ⅰ类MHC多肽相关序列A(MICA)活性蛋白 | 重组人 MICA 蛋白

MIC-A | HLA class I antigen | FLJ36918 | FLJ60820 | MGC111087 | MGC21250 | MHC class I chain related gene A protein | MHC class I chain related protein A | MHC class I chain related protein A HLA B HLA C | MHC class I polypeptide related sequence A | MHC

rp148798-10μg

10μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Immobilized Recombinant Human MICA Protein (rp148798) at 2.0 μg/mL can bind Human NKG2D with the ED50 for this effect is 12.22 ng/mL.

重组表达

36 kDa

C-His

50 - 65 kDa, under reducing conditions; 50 - 65 kDa, under non-reducing conditions.

HEK293 Accession #: Q29983 | HEK293

<0.1 EU/μg

人(Human)

1-308 aa

MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQHHHHHH

Yes

Yes