Recombinant Human Neuroserpin Protein

重组人神经丝氨酸蛋白 | 重组人类神经丝氨酸蛋白酶抑制剂蛋白

DKFZp781N13156 | Neuroserpin | NEUS_HUMAN | Peptidase inhibitor 12 | PI-12 | PI12 | Protease inhibitor 12 | Serine or cysteine proteinase inhibitor clade I (neuroserpin) member 1 | Serine or cysteine proteinase inhibitor clade I member 1 | Serpin I1 | Ser

rp149226-50μg

50μg

无动物源

≥95%(SDS-PAGE&HPLC)

＞95%(SDS-PAGE and HPLC)

Purity > 95% by SDS-PAGE and HPLC analyses. Function Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

Fully biologically active when compared to standard. The ED₅₀ as determined by a cell proliferation assay using rat C6 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2000 IU/mg.

重组表达

44.7 kDa

No tag

Full length protein

E. coli Accession #: Q99574 | E. coli

<1.0 EU/μg

人(Human)

17-410 aa

TGATFPEEAI ADLSVNMYNR LRATGEDENI LFSPLSIALA MGMMELGAQG STQKEIRHSM GYDSLKNGEE FSFLKEFSNM VTAKESQYVM KIANSLFVQN GFHVNEEFLQ MMKKYFNAAV NHVDFSQNVA VANYINKWVE NNTNNLVKDL VSPRDFDAAT YLALINAVYF KGNWKSQFRP ENTRTFSFTK DDESEVQIPM MYQQGEFYYG EFSDGSNEAG GIYQVLEIPY EGDEISMMLV LSRQEVPLAT LEPLVKAQLV EEWANSVKKQ KVEVYLPRFT VEQEIDLKDV LKALGITEIF IKDANLTGLS DNKEIFLSKA IHKSFLEVNE EGSEAAAVSG MIAISRMAVL YPQVIVDHPF FFLIRNRRTG TILFMGRVMH PETMNTSGHD FEEL

Yes

Yes