Recombinant Human NKp30/NCR3 Protein

重组人NKp30/NCR3蛋白 | 重组人自然细胞毒性触发受体3蛋白

Activating natural killer receptor p30 | Natural killer cell p30-related protein | NKp30 | NK-p30 | CD337 antigen | Activating natural killer receptor p30 | CD337 | CD337activating NK-A1 receptor | LY117 | 1C7 | NK-p30 | lymphocyte antigen 117 | natural c

rp149312-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Measured by its binding ability in a functional ELISA. When Recombinant Human B7-H6 Fc Chimera is immobilized at 4 µg/mL (100 µL/well), Recombinant Human NKp30/NCR3 His-tag binds with an ED50 of 0.600-7.20 µg/mL.

重组表达

14 kDa

C-His

20 - 35 kDa, under reducing conditions; 20 - 35 kDa, under non-reducing conditions.

HEK293 Accession #: O14931-1 | HEK293

<0.1 EU/μg

人(Human)

19-138 aa

LWVSQPPEIRTLEGSSAFLPCSFNASQGRLAIGSVTWFRDEVVPGKEVRNGTPEFRGRLAPLASSRFLHDHQAELHIRDVRGHDASIYVCRVEVLGLGVGTGNGTRLVVEKEHPQLGAGTHHHHHH

Yes

Yes