Recombinant Human SF20/MYDGF Protein

重组人SF20/MYDGF蛋白 | 重组人骨髓源性生长因子蛋白

MYDGF | Stromal Cell-derived Growth Factor SF20 | C19orf10 | chromosome 19 open reading frame 10 | EUROIMAGE1875335 | IL25 | IL27 | IL27w | interleukin 27 working designation | interleukin-25 | Ly6elg | MYDGF | myeloid-derived growth factor | R33729_1 | S

rp151474-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.

Measured by its binding ability in a functional ELISA. When Recombinant Human SF20/MYDGF is immobilized at 2 μg/mL (100 μL/well), Recombinant Human Protein Disulfide Isomerase/P4HB binds with an ED50 of 0.8-4.8 μg/mL.

重组表达

16 kDa

C-His

15 kDa, under reducing conditions; 15 kDa, under non-reducing conditions.

HEK293 Accession #: Q969H8 | HEK293

<0.1 EU/μg

人(Human)

32-173 aa

VSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRTELHHHHHH

Yes

Yes