Recombinant Human TNFRSF1A Protein

重组人TNFRSF1A蛋白 | 重组人 TNFRSF1A 蛋白

CD120a antigen | CD120a | FPF | p55 | p55-R | p60 | TNF RI | TNFARMGC19588 | TNF-R | TNF-R1 | TNFR1TBP1 | TNFR55 | TNF-R55 | TNFR60 | TNFRI | TNF-RI | TNF-R-I | TNFR-I | TNFRSF1A | tumor necrosis factor binding protein 1 | Tumor necrosis factor receptor 1

rp152513-50μg

50μg

无动物源

≥97%(SDS-PAGE&HPLC)

＞97%(SDS-PAGE, HPLC)

Purity > 97 % by SDS-PAGE and HPLC analyses. Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.

重组表达

21.2 kDa

No tag

Protein fragment

E. coli Accession #: P19438 | E. coli

<0.1 EU/μg

人(Human)

22-211 aa

IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT

Yes

Yes