Recombinant Human CD40 Ligand/TNFSF5 Protein

重组人CD40配体蛋白 | 重组人 CD40 配体/TNFSF5 蛋白

CD154 antigen | CD154 | CD40 antigen ligand | CD40 Ligand | CD40L | CD40-L | CD40LG | CD40LIGM | gp39 | hCD40L | HIGM1 | T-B cell-activating molecule | T-BAM | T-cell antigen Gp39 | TNF-related activation protein | TNFSF5 | TNFSF5IMD3 | TRAP | TRAPtumor n

rp152636-50μg

50μg

无动物源

≥95%(SDS-PAGE&HPLC)

>95% (SDS-PAGE&HPLC)

Purity >95% (SDS-PAGE&HPLC) Endotoxin level Function Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.

重组表达

16.3 kDa

No tag

16.3 kDa

E. coli Accession #: P29965 | E. coli

<1.0 EU/μg

人(Human)

113-263 aa

MQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLWLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL

Yes

Yes