Recombinant Human TrkC Protein

重组人TrkC蛋白 | 重组人神经酪氨酸激酶受体3蛋白

EC 2.7.10 | EC 2.7.10.1 | ETS related protein-neurotrophic receptor tyrosine kinase fusion protein | ETV6-NTRK3 fusion | gp145(trkC) | GP145-TrkC | Neurotrophic tyrosine kinase receptor type 3 | neurotrophic tyrosine kinase, receptor, type 3 | NT 3 recept

rp152729-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.

Measured by its ability to inhibit NT-3-induced proliferation of BaF‑TrkB‑BD mouse pro‑B cells transfected with TrkB. The ED50 for this effect is 0.05-0.2 µg/mL in the presence of 40 ng/mL of rhNT-3.

重组表达

72 kDa

C-hFc & His

100 - 125 kDa, under reducing conditions; 230 - 300 kDa, under non-reducing conditions.

HEK293 Accession #: Q96CY4 | HEK293

<0.1 EU/μg

人(Human)

32-428 aa

CPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

Yes

Yes