Recombinant Mouse CD14 Protein

重组小鼠单核细胞分化抗原CD14蛋白 | 重组小鼠CD14蛋白

CD 14 | CD_antigen=CD14 | CD14 | CD14 antigen | CD14 molecule | CD14_HUMAN | LPS-R | Mo2 | Monocyte differentiation antigen CD14 | Monocyte differentiation antigen CD14 urinary form | Monocyte differentiation antigen CD14, membrane-bound form | Myeloid ce

rp153710-2μg

2μg

无动物源

≥95%(SDS-PAGE)

＞95%(SDS-PAGE)

Purity >90% SDS-PAGE. Additional sequence information This product is for the mature full length protein. The signal peptide is not included. NP_033971 Function Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. Post-translational N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.

Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED50 for this effect is 0.4-2.4 µg/mL.

重组表达

62 kDa

C-hFc & His

HEK293 Accession #: Q4FJP7 | HEK293

<0.01 EU/μg

小鼠(Mouse)

18-345 aa

APPEPCELDEESCSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAGAPSCDWPSQLNSLNLSFTGLKQVPKGLPAKLSVLDLSYNRLDRNPSPDELPQVGNLSLKGNPFLDSESHSEKFNSGVVTAGAPENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

Yes

Yes