Recombinant Mouse CD25/IL-2R alpha Protein

重组小鼠CD25/IL-2R alpha蛋白 | 重组小鼠白介素2受体α蛋白

Interleukin 2 Receptor alpha | CD25 antigen | CD25 | IDDM10 | IL-2 R alpha | IL-2 receptor subunit alpha | IL2R alpha | IL-2R subunit alpha | IL2R | IL2RA | IL-2Ra | IL-2-RA | IL2-RA | interleukin 2 receptor, alpha | interleukin-2 receptor subunit alpha |

rp154176-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.045-0.3 µg/mL in the presence of 30 ng/mL of recombinant human IL-2.

重组表达

26 kDa

C-10His

40-50 kDa under reducing conditions.

HEK293 Accession #: Q544I2 | HEK293

<0.1 EU/μg

小鼠(Mouse)

22-236 aa

ELCLYDPPEVPNATFKALSYKNGTILNCECKRGFRRLKELVYMRCLGNSWSSNCQCTSNSHDKSRKQVTAQLEHQKEQQTTTDMQKPTQSMHQENLTGHCREPPPWKHEDSKRIYHFVEGQSVHYECIPGYKALQRGPAISICKMKCGKTGWTQPQLTCVDEREHHRFLASEESQGSRNSSPESETSCPITTTDFPQPTETTAMTETFVLTMEYKHHHHHHHHHH

Yes

Yes