Recombinant Mouse IL-23R Protein

介素23受体(IL23R)重组蛋白

IBD17 | IL-23 R | IL-23 receptor | IL23R | IL-23R | interleukin 23 receptor | interleukin-23 receptor

rp154193-10μg

10μg

无动物源

≥90%(SDS-PAGE)

功能 与 IL12RB1 结合形成白细胞介素-23 受体。与 IL23 结合，可能通过激活 Jak-Stat 信号级联，介导对 T 细胞、NK 细胞以及某些巨噬细胞/骨髓细胞的刺激。IL23 在先天性免疫和适应性免疫中发挥作用，可能参与外周组织对感染的急性反应。IL23 可能是自身免疫性炎症疾病的罪魁祸首，对肿瘤发生也很重要。

Measured by its binding ability in a functional ELISA. When Recombinant Mouse IL-23 R is immobilized at 5 µg/mL (100 µL/well) the concentration of Recombinant Mouse IL‑23 that produces 50% of optimal binding response is approximately 5-25 ng/mL.

重组表达

41 kDa

C-His

55 - 80 kDa, under reducing conditions; 55 - 80 kDa, under non-reducing conditions.

HEK293 Accession #: Q8K4B4 | HEK293

<0.1 EU/μg

小鼠(Mouse)

24-372 aa

GITSINCSGDMWVEPGEIFQMGMNVSIYCQEALKHCRPRNLYFYKNGFKEEFDITRINRTTARIWYKGFSEPHAYMHCTAECPGHFQETLICGKDISSGHPPDAPSNLTCVIYEYSGNMTCTWNTGKPTYIDTKYIVHVKSLETEEEQQYLASSYVKISTDSLQGSRKYLVWVQAVNSLGMENSQQLHVHLDDIVIPSASIISRAETTNDTVPKTIVYWKSKTMIEKVFCEMRYKTTTNQTWSVKEFDANFTYVQQSEFYLEPDSKYVFQVRCQETGKRNWQPWSSPFVHQTSQETGKRNWQPWSSPFVHQTSQTVSQVTAKSSHEPQKMEMLSATIFRGHPASGNHQDHHHHHH

Yes

Yes