Recombinant Mouse SLAM/CD150 Protein

重组小鼠SLAM/CD150蛋白 | 重组小鼠信号淋巴细胞激活分子家族成员1蛋白

Signaling Lymphocytic Activation Molecule | CD 150 | CD150 | IPO-3 | CDw150 | signaling lymphocytic activation molecule family member 1 | SLAM | CD150 antigen | SLAMF1 | ESTM51 | 4933415F16

rp154665-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

Measured by its ability to co-stimulate IL-4 secretion by D10.G4.1 mouse helper T cells in the presence of anti-CD3. The ED50 for this effect is 0.6-2.4 μg/mL.

重组表达

25 kDa

C-His

41-55 kDa under reducing conditions.

HEK293 Accession #: Q9QUM4-1 | HEK293

<0.1 EU/μg

小鼠(Mouse)

25-242 aa

TGGGVMDCPVILQKLGQDTWLPLTNEHQINKSVNKSVRILVTMATSPGSKSNKKIVSFDLSKGSYPDHLEDGYHFQSKNLSLKILGNRRESEGWYLVSVEENVSVQQFCKQLKLYEQVSPPEIKVLNKTQENENGTCSLLLACTVKKGDHVTYSWSDEAGTHLLSRANRSHLLHITLSNQHQDSIYNCTASNPVSSISRTFNLSSQACKQESSSESSPHHHHHH

Yes

Yes