Recombinant Mouse Coagulation Factor III/Tissue Factor Protein

组织因子(TF)重组蛋白

CD142 antigen | CD142 | coagulation factor III (thromboplastin, tissue factor) | Coagulation Factor III | F3 | FLJ17960 | TF | TFA | Thromboplastin | Tissue Factor | Cf3 | Cf-3

rp154747-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or × by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

Measured by its ability to activate Coagulation Factor VII in cleaving a fluorogenic peptide substrate Boc-VPR-AMC. The AC50 is <5 µg/mL, as measured under the described conditions.

重组表达

26 kDa

C-His

35 - 45 kDa, under reducing conditions; 35 - 45 kDa, under non-reducing conditions.

HEK293 Accession #: P20352 | HEK293

<0.1 EU/μg

小鼠(Mouse)

29-251 aa

AGIPEKAFNLTWISTDFKTILEWQPKPTNYTYTVQISDRSRNWKNKCFSTTDTECDLTDEIVKDVTWAYEAKVLSVPRRNSVHGDGDQLVIHGEEPPFTNAPKFLPYRDTNLGQPVIQQFEQDGRKLNVVVKDSLTLVRKNGTFLTLRQVFGKDLGYIITYRKGSSTGKKTNITNTNEFSIDVEEGVSYCFFVQAMIFSRKTNQNSPGSSTVCTEQWKSFLGEHHHHHHFSTTDTECDLTDEIVKDVTWAYEAKVLSVPRRNSVHGDGDQLVIHGEEPP FTNAPKFLPYRDTNLGQPVIQQFEQDGRKLNVVVKDSLTLVRKNGTFLTL RQVFGKDLGYIITYRKGSSTGKKTNITNTNEFSIDVEEGVSYCFFVQAMI FSRKTNQNSPGSSTVCTEQWKSFLGEHHHHHH

Yes

Yes