Recombinant Rat VEGF 164 Protein

重组大鼠VEGF 164蛋白 | 重组大鼠血管内皮生长因子A蛋白

Vascular Endothelial Growth Factor | MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VEGF-A | MGC70609 | VPF | VEGF111 | VEGF164

rp155249-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.

Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 0.75‑3.75 ng/mL.

重组表达

19.2 kDa

No tag

22 - 28 kDa, under reducing conditions; 40 - 46 kDa, under non-reducing conditions.

HEK293 Accession #: P16612-2 | HEK293

<0.1 EU/μg

大鼠(Rat)

27-190 aa

APTTEGEQKAHEVVKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNVTMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPENHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR

Yes

Yes