Recombinant MPXV A35R Protein

猴痘病毒 | 猴痘病毒 A35R | 猴痘A35R蛋白 | 重组猴痘病毒 A35R 蛋白

A35R | OPG161 EEV glycoprotein | OPG161 | MPVX A35R | Monkeypox virus | Monkeypox virus A35R

rp155843-1mg

1mg

无载体

≥95%(SDS-PAGE)

＞95% (SDS-PAGE)

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. A35R gene is highly conserved among poxviruses and encodes a previously uncharacterized hydrophobic acidic protein. The A35R has little homology to any protein outside of poxviruses, suggesting a novel virulence Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. A35R gene is highly conserved among poxviruses and encodes a previously uncharacterized hydrophobic acidic protein. The A35R has little homology to any protein outside of poxviruses, suggesting a novel virulence mechanism.A35R could block some stage of antigen processing or presentation in infected cells or interfere with regulation of apoptosis. In addition, the A35R function may be required for growth in certain cell types, e.g., macrophage, in vivo. It localizes to factories where viral DNA is located and it was shown to be a constitutive transcriptional activator in a large-scale yeast two-hybrid study.

重组表达

16.0 kDa

N-His

15.5 kDa, under reducing conditions; 33.0 kDa, under non-reducing conditions.

E. coli Accession #: Q8V4U4 | E. coli

猴痘病毒(Monkeypox virus)

58-181 aa

MGSSHHHHHHSSGLVPRGSHMRQNQCMSANEAAITDSAVAVAAASSTHRKVASSTTQYDHKESCNGLYYQGSCYILHSDYKSFEDAKANCAAESSTLPNKSDVLTTWLIDYVEDTWGSDGNPITKTTSDYQDSDVSQEVRKYFCT.

Yes